Research Gap Identification in Biotechnology
Description
1. Genetic Engineering and Modification
1.1. Ethical Implications of Gene Editing in Humans
1.2. Long-term Effects of Genetically Modified Organisms (GMOs)
1.3. Enhancing CRISPR-Cas9 Precision and Off-target Effects
2. Biopharmaceuticals
2.1. Personalized Medicine Approaches in Drug Development
2.2. Development of Novel Drug Delivery Systems for Biologics
2.3. Immunogenicity and Allergic Reactions to Biopharmaceuticals
3. Bioinformatics and Computational Biology
3.1. Advancements in Predictive Genomic Analysis
3.2. Big Data Analytics for Biological Data Interpretation
3.3. Privacy and Security Concerns in Genomic Data Sharing
4. Synthetic Biology
4.1. Standardization of Biological Parts and Devices
4.2. Creating Artificial Life: Ethical and Moral Implications
4.3. Environmental Impact Assessment of Synthetic Microorganisms
5. Bioprocessing and Biomanufacturing
5.1. Scalability Challenges in Bioproduction
5.2. Continuous Bioprocessing vs. Batch Processing: Optimization
5.3. Sustainability and Green Techniques in Biomanufacturing
6. Bioenergy and Environmental Biotechnology
6.1. Enhancing Microbial Fuel Cell Efficiency
6.2. Biomass Conversion Technologies: Cost-effectiveness
6.3. Bioremediation Strategies for Emerging Pollutants
7. Medical Biotechnology
7.1. Stem Cell Therapy: Standardization and Safety
7.2. CRISPR-based Therapeutics: Delivery Challenges
7.3. Biotechnology Interventions in Cancer Immunotherapy
8. Plant Biotechnology
8.1. Drought and Salinity Tolerance in Genetically Modified Crops
8.2. Crop Disease Resistance: Sustainable Approaches
8.3. Impact of GM Crops on Biodiversity and Ecosystems
9. Industrial Biotechnology
9.1. Enzyme Engineering for Industrial Applications
9.2. Bioplastics: Enhancing Production and Biodegradability
9.3. Microbial Biofactories for Chemical Production
10. Ethical, Legal, and Social Implications (ELSI) of Biotechnology
10.1. Ensuring Equitable Access to Biotechnological Advancements
10.2. Regulatory Frameworks for Gene-edited Organisms
10.3. Public Perception and Understanding of Biotechnological Innovations
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