Loading Video...
NTHRYS
Arrow

Bayesian Therapeutic Drug Monitoring & Dosing Training | TDM, Priors & Precision Dosing

NTHRYS >> Services >> Academic Services >> Training Programs >> Bioinformatics Training >> Pharmacogenomics, Pharmacometrics & Precision Therapeutics >> Bayesian Therapeutic Drug Monitoring & Dosing Training | TDM, Priors & Precision Dosing

Bayesian Therapeutic Drug Monitoring and Dosing — Hands-on

Understand how Bayesian therapeutic drug monitoring (TDM) supports precision dosing. This module focuses on the conceptual workflow: starting from prior knowledge and patient data, updating a PK model in a Bayesian way, reading posterior exposure, and drafting dose recommendations and follow up plans for clinicians.

Bayesian Therapeutic Drug Monitoring and Dosing
Help Desk · WhatsApp
Session 1
Fee: Rs 8800
TDM & Bayesian Thinking Foundations
  • Role of therapeutic drug monitoring in clinical practice
  • narrow therapeutic index drugs toxicity and failure prevention integration with clinical judgement
  • Classical vs Bayesian TDM thinking
  • fixed trough ranges idea patient specific PK model concept prior, data and posterior view
  • High level TDM–Bayesian workflow overview
  • collect context and sample timing update model with levels translate to dosing advice
Session 2
Fee: Rs 11800
Data, Priors & Posterior Exposure
  • Concentration–time data and sampling concepts
  • peak, trough and random levels steady state assumptions recording dose and sampling history
  • Priors and PK models at a conceptual level
  • population parameter expectations between subject variability idea using prior information responsibly
  • Posterior exposure and prediction thinking
  • updated individual PK profile concept visualizing predicted concentration curves credible intervals and uncertainty
Session 3
Fee: Rs 14800
Bayesian Dosing Decisions & Follow Up
  • From posterior exposure to dose adjustment ideas
  • target concentration windows concept changing dose or interval themes balancing efficacy and safety signals
  • Special situations in Bayesian TDM (high level)
  • renal and hepatic impairment ideas obesity and critical illness themes drug interactions and changing clearance
  • Sequential TDM and communication with the team
  • planning next sample timing documenting rationale and caveats integrating feedback from outcomes
Session 4
Fee: Rs 18800
Mini Capstone: TDM–Bayesian Dose Consult
  • Assemble a TDM case with context and level data
  • summarize indication and comorbidities list dose history and samples note interacting medicines and organ function
  • Draft a Bayesian TDM dosing recommendation
  • describe inferred exposure pattern conceptually propose new dose or interval outline monitoring and re sampling plan
  • Deliverables: TDM–Bayesian consult note and slide
  • clinic note as PDF or DOCX one slide summary for boards template for future TDM cases


PDF