Capstone — End-to-End Glycomics Project — Mentored

Bring together your learning from the glycomics track in a guided end to end project. From scoping a biological or clinical question and planning a glycomics workflow through LC–MS data processing, glycan annotation, statistical analysis and reporting, you will complete a mentored mini project that generates a reusable dataset and publication ready outputs.

Capstone — End-to-End Glycomics Project

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Session Index

Session 1 — Project Scoping and Study Design Session 2 — Data Processing and Glycan Annotation Session 3 — Statistics, Visualization and Interpretation Session 4 — Final Report and FAIR Submission Pack

Session 1

Fee: Rs 8800

Project Scoping and Study Design

Selecting a biological or clinical use case for glycomics

immune and inflammation context cancer or metabolic disease angle bioprocess or quality control scenario

Designing the end to end glycomics workflow

sample type and platform choice (LC–MS, MALDI, NMR dataset) defining controls and comparison groups planning QC samples and replicates

Setting objectives, milestones and deliverables

primary and secondary questions timeline and task breakdown templates for data and metadata tracking

Session 2

Fee: Rs 11800

Data Processing and Glycan Annotation

Working with a provided raw glycomics dataset

importing LC–MS or MALDI files peak detection and integration concepts alignment and batch checks at overview level

Glycan identification and annotation steps

matching to library or database assigning compositions and structures building a tidy sample by glycan matrix

QC, normalization and feature derivation

removing unstable or low quality features normalizing intensities or areas calculating glycan traits such as sialylation and fucosylation

Session 3

Fee: Rs 14800

Statistics, Visualization and Interpretation

Exploratory statistics and group comparisons

PCA or clustering for pattern discovery basic differential glycan analysis simple multiple testing control concepts

Visualizing glycan signatures and traits

heatmaps and profile plots trait level bar and radar plots co variation plots with simple clinical variables

Biological and pathway interpretation of findings

linking changes to biosynthesis steps and enzymes relating patterns to disease or process mechanisms identifying candidate biomarkers or targets

Session 4

Fee: Rs 18800

Final Report and FAIR Submission Pack

Structuring the project notebook and narrative

Theory plus Practical

Preparing figures, tables and summary slides

key plots for main results summary tables of glycan traits and statistics short presentation deck for review

Building a mini FAIR style data and metadata bundle

cleaned data matrix and code files metadata and methods description list of next steps and potential manuscript outline

PDF

Capstone End-to-End Glycomics Project Training | Design, Analyze and Report

Capstone — End-to-End Glycomics Project — Mentored