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Capstone Pharmacogenomics & PMx Project Training | End-to-End Genotype-to-Dose

NTHRYS >> Services >> Academic Services >> Training Programs >> Bioinformatics Training >> Pharmacogenomics, Pharmacometrics & Precision Therapeutics >> Capstone Pharmacogenomics & PMx Project Training | End-to-End Genotype-to-Dose

Capstone — End-to-End Pharmacogenomics & PMx Project — Hands-on

Apply everything learned across pharmacogenomics and pharmacometrics into a guided, end-to-end project. In this capstone, you will frame a PGx–PMx use case, assemble and interrogate datasets, structure a conceptual PK/PD reasoning path, and prepare a clear genotype-to-dose decision-support report with audit-ready documentation.

Capstone — End-to-End Pharmacogenomics & PMx Project
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Session 1
Fee: Rs 8800
Use-Case Framing & Data Landscape
  • Selecting a PGx–PMx use case and clinical context
  • high-impact drug–gene pair indication and line of therapy clear clinical decision question
  • Mapping the data landscape for the project (conceptual)
  • PGx results and phenotypes dose, exposure and outcome records basic covariates and comedications
  • Drafting a one-page project charter
  • objectives and key questions scope, assumptions and constraints simple milestones and timelines
Session 2
Fee: Rs 11800
PGx Interpretation & PMx Reasoning
  • Summarising pharmacogene findings for the chosen case
  • genotype to phenotype translation conceptual use of guideline tiers baseline risk narrative for the patient
  • Structuring a PK/PD and exposure–response reasoning path
  • clearance and exposure expectations effect window and toxicity window ideas impact of covariates in plain language
  • Aligning PGx interpretation with dose and regimen options
  • candidate starting dose bands when to avoid or switch medicines initial monitoring and follow-up plans
Session 3
Fee: Rs 14800
Integrated Workflow & Mock Outputs
  • Designing the end-to-end PGx–PMx workflow on paper
  • from sample and data intake to report key checkpoints and handshakes simple swimlane diagram for teams
  • Preparing mock analytic and decision-support outputs
  • tables and plots that summarise exposure PGx-aware dose recommendation block notes for EMR or report integration
  • Capturing rationale, assumptions and limitations clearly
  • what data were used and not used strength of evidence narrative when to revisit or update decisions
Session 4
Fee: Rs 18800
Final Showcase & Audit Trail
  • Presenting the genotype-to-dose recommendation to peers
  • 5–10 minute oral presentation single-slide clinical summary Q&A from a mixed audience
  • Building a simple audit trail for the project
  • versioned artefacts and logs list decision and assumption register hand-over note for future work
  • Deliverables: PGx–PMx project dossier and reflection note
  • PDF or PPTX dossier 1–2 page written reflection portfolio-ready project summary


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