Capstone — End-to-End Systems Biology Project — Hands-on

Consolidate everything learnt in systems biology, network medicine and pathway modeling into a single guided capstone. You will scope a realistic problem, assemble data, design and implement a mechanistic or network based workflow, perform calibration or analysis and deliver a transparent report and sharable model bundle.

Capstone — End-to-End Systems Biology Project

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Session Index

Session 1 — Problem Scoping, Data & Model Blueprint Session 2 — Network / Mechanistic Model Construction Session 3 — Calibration, Analysis & Scenario Runs Session 4 — Packaging, Reporting & Presentation

Session 1

Fee: Rs 8800

Problem Scoping, Data & Model Blueprint

Define a focused systems biology or network medicine question

pathway or disease mechanism of interest clear outcome and decision context success criteria and constraints

Select data and knowledge sources for the project

omics and literature based inputs network and pathway resources clinical or phenotype context where relevant

Draft a model or network blueprint and workflow plan

choice of network or ODE or hybrid style inputs outputs and evaluation plan timeline and milestone checklist

Session 2

Fee: Rs 11800

Network / Mechanistic Model Construction

Assemble and curate the core network or model structure

interaction and reaction level curation consistency with pathway databases documented assumptions and simplifications

Implement the model in a reusable format and toolchain

SBML or equivalent script based form notebooks or scripts for simulation basic unit and sanity checks

Initial parameterisation or network scoring choices

literature or database based parameter guesses initial conditions and input settings first round simulations and quick plots

Session 3

Fee: Rs 14800

Calibration, Analysis & Scenario Runs

Calibrate or tune the model against selected data

simple parameter estimation loop fit quality and residual inspection basic sensitivity or robustness checks

Run key scenarios and summarise system behaviour

baseline and perturbation cases network or pathway output summaries figures that answer the main question

Link model readouts to potential interventions or hypotheses

prioritised levers and targets expected qualitative or quantitative effects caveats and remaining uncertainties

Session 4

Fee: Rs 18800

Packaging, Reporting & Presentation

Prepare a reproducible project and model bundle

scripts or notebooks with clear order SBML or network files plus configs minimal environment description

Write a concise systems biology project report

question methods and data summary results and key figures interpretation and next steps

Deliverables and oral walkthrough of the project

slide deck or summary notebook project repository or archive file mentor feedback and grading rubric

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Capstone: End-to-End Systems Biology Project Training | Applied Systems Biology & Network Medicine

Capstone — End-to-End Systems Biology Project — Hands-on