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Capstone — Translational Genomics Project | End-to-End Pipeline, Analysis & Submission Bundle

NTHRYS >> Services >> Academic Services >> Training Programs >> Bioinformatics Training >> Genomics, Transcriptomics, Molecular Systems >> Capstone — Translational Genomics Project | End-to-End Pipeline, Analysis & Submission Bundle

Capstone — Translational Genomics Project

Design, implement, and defend an end-to-end translational genomics project—data strategy, automated pipelines, analysis & interpretation, and submission-ready reporting.

Capstone — Translational Genomics Project
Help Desk · WhatsApp
Session 1
Fee: Rs 6300
Proposal & Data Strategy
  • Clinical question framing, outcomes, cohort design, consent & ethics
    • Theory
  • Data inventory, formats, metadata model, and governance plan
    • FAIR BioProject/BioSample ENA/GEO/SRA
  • Risk register, milestones, KPIs and acceptance criteria
    • RACI Issue Tracker Change Log
Session 2
Fee: Rs 8400
Pipeline Build & Automation
  • QC→align/assemble→call→annotate staged pipeline with configs
    • Snakemake/Nextflow Conda/Mamba Docker/Apptainer
  • Parameterization, profiles, CI/CD and run provenance capture
    • GitHub Actions MLflow/W&B checksum manifests
  • Dashboards and alerts for QC and runtime metrics
    • MultiQC Quarto JupyterLab
Session 3
Fee: Rs 11200
Analysis, Visualization & Validation
  • Differential expression/variant interpretation & pathway mapping
    • DESeq2/edgeR VEP/ANNOVAR GSEA/Reactome
  • Figures, tables and interactive notebooks for review
    • ggplot2/plotly Quarto JupyterLab
  • Validation checks, manual review & sign-off criteria
    • IGV QC gates Audit Trail
Session 4
Fee: Rs 14000
Final Defense & Submission
  • Oral defense with live demo and Q&A on design decisions
    • Theory + Practical
  • Export submission-ready bundle with provenance and metadata
    • RO-Crate/BagIt ENA/GEO/SRA PDF/CSV/TSV
  • Final report, checklist, and sign-off package
    • Quarto Zenodo DOI Change Log


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