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Causal Inference & Intervention Design Training | FMT, Diet & Microbiome Trials

NTHRYS >> Services >> Academic Services >> Training Programs >> Bioinformatics Training >> Microbiome, Metagenomics & Microbial Systems Biology >> Causal Inference & Intervention Design Training | FMT, Diet & Microbiome Trials

Causal Inference & Intervention Design FMT Diet — Hands-on

Learn how to move beyond correlation and design microbiome studies that target causal questions. You will work with causal diagrams, understand confounding and bias, apply propensity based frameworks, and translate findings into interpretable effect estimates for FMT, diet, probiotic and other microbiome focused interventions.

Causal Inference and Intervention Design FMT Diet
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Session 1
Fee: Rs 8800
Causal Inference Concepts in Microbiome Studies
  • From association to causation in microbiome research
  • correlation vs causal effect counterfactual thinking estimands and effect measures
  • Causal diagrams and bias structures in microbiome studies
  • directed acyclic graphs ideas confounders, mediators and colliders backdoor paths and adjustment sets
  • Study design options for causal microbiome questions
  • randomized trials and cross over ideas observational cohorts and registries natural experiments and opportunistic designs
Session 2
Fee: Rs 11800
Confounding Control & Effect Estimation Frameworks
  • Confounding and selection bias in microbiome interventions
  • baseline imbalance and risk factors loss to follow up thinking measurement and misclassification issues
  • Adjustment strategies and propensity style frameworks
  • regression adjustment and stratification ideas propensity scores, matching and weighting concepts balance diagnostics mindset
  • Effect estimation and sensitivity thinking
  • average treatment effect style summaries subgroup and heterogeneous effects sensitivity to unmeasured confounding
Session 3
Fee: Rs 14800
FMT, Diet and Probiotic Intervention Design
  • Designing FMT and microbiome directed trials conceptually
  • donor and recipient selection logic randomization, blinding and controls safety, ethics and follow up windows
  • Dietary and probiotic intervention frameworks
  • exposure definition and adherence tracking time varying exposures and co interventions choice of primary and secondary outcomes
  • Linking causal estimands to microbiome readouts
  • alpha and beta diversity as responses taxa, pathways and summary scores responder and non responder patterns
Session 4
Fee: Rs 18800
Mini Capstone: Microbiome Intervention Analysis
  • End to end analysis of an example microbiome intervention
  • Theory plus guided practical
  • Summarizing causal effects and uncertainties for decision makers
  • effect size tables and plots subgroup and sensitivity summaries transparent reporting of assumptions
  • Deliverables: analysis notebook, effect summaries & methods block
  • tidy analysis tables figures for reports and slides reusable causal analysis methods text


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