Clinical & Nutrimetabolomics — Biomarker Panels — Hands-on

Learn how to design, analyse and interpret clinical and nutrition focused metabolomics studies for biomarker discovery and translational applications. This module covers study design, sample handling, dietary exposure capture, biomarker panel development, validation and reporting so that your outputs are ready for clinicians, nutrition scientists and regulatory review.

Clinical & Nutrimetabolomics — Biomarker Panels

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Session Index

Session 1 — Clinical & Nutrimetabolomics Foundations Session 2 — Study Design, Sampling & Pre Analytical Variables Session 3 — Biomarker Discovery, Panels & Validation Session 4 — Mini Capstone: Clinical Nutrition Biomarker Panel

Session 1

Fee: Rs 8800

Clinical & Nutrimetabolomics Foundations

Role of metabolomics in clinical and nutrition research

disease diagnosis and prognosis treatment response and therapy monitoring dietary exposure and nutritional status

Matrices and assay types in clinical metabolomics

plasma, serum, urine, dried blood spots targeted vs untargeted approaches panel based assays and reference labs

Basic concepts in biomarker and panel development

risk stratification and cut offs single analyte vs multi analyte panels fit for purpose validation levels

Session 2

Fee: Rs 11800

Study Design, Sampling & Pre Analytical Variables

Clinical and nutrition study designs for metabolomics

case control, cohort and longitudinal designs dietary intervention and challenge tests time points and sampling schedules

Pre analytical variation and standardisation

fasting vs non fasting collection processing delays and storage conditions freeze thaw cycles and stability

Dietary assessment and contextual data capture

food frequency and recalls (overview) linking dietary data with metabolome covariates and confounders for models

Session 3

Fee: Rs 14800

Biomarker Discovery, Panels & Validation

Feature level statistics and candidate selection

group comparisons and effect sizes adjustment for covariates false discovery control in clinical data

Building and evaluating biomarker panels

logistic regression and ML classifiers ROC, AUC, sensitivity and specificity calibration, decision curves and risk groups

Validation strategies and translation considerations

internal vs external validation sets orthogonal and targeted follow up assays pre analytical and population generalisability

Session 4

Fee: Rs 18800

Mini Capstone: Clinical Nutrition Biomarker Panel

End to end workflow on a teaching dataset

from processed matrix to biomarker panel

Translating model outputs into clinical language

risk categories and cut offs plots and tables for clinicians and nutritionists limitations and next steps section

Deliverables: panel table, figures & methods text

biomarker list with model coefficients ROC and calibration plots bundle ready to edit clinical metabolomics methods

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Clinical & Nutrimetabolomics — Biomarker Panels Training | Study Design & Clinical Panels

Clinical & Nutrimetabolomics — Biomarker Panels — Hands-on