Clinical Proteomics & Biomarker Discovery — Hands-on

Build a strong conceptual understanding of clinical proteomics and biomarker discovery. This module focuses on study types, cohort and sample design, quantitative readouts and performance metrics, and how proteomic signatures can be translated into candidate biomarker panels and clinical decision support concepts.

Clinical Proteomics & Biomarker Discovery

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Session Index

Session 1 — Clinical Proteomics & Biomarker Foundations Session 2 — Cohort Design, Samples & Pre-analytics Session 3 — Quantitative Readouts & Performance Metrics Session 4 — Mini Capstone: Biomarker Study & Panel Plan

Session 1

Fee: Rs 8800

Clinical Proteomics & Biomarker Foundations

Role of proteomics in clinical research and diagnostics

disease classification concepts prognostic and predictive markers pharmacoproteomics idea

Biomarker discovery, verification and validation (conceptual)

discovery vs targeted phases single markers vs panels fit for purpose thinking

Translational and regulatory context at high level

analytical vs clinical validation ideas clinical utility and decision impact overview of lab quality and standards

Session 2

Fee: Rs 11800

Cohort Design, Samples & Pre-analytics (Concepts)

Cohort design and clinical question framing (idea level)

case–control vs longitudinal concepts inclusion and exclusion thinking confounders and stratification ideas

Clinical sample types and matrices at conceptual level

plasma / serum / urine / CSF overview tissue and FFPE ideas analyte stability concepts

Pre-analytical variables and biobanking considerations (concepts)

collection, processing and storage ideas freeze–thaw and hemolysis awareness linking metadata to proteomic readouts

Session 3

Fee: Rs 14800

Quantitative Readouts & Performance Metrics (Concepts)

Discovery vs targeted quantitative strategies (high level)

label free and labeled ideas relative vs absolute quantification concepts internal standard thinking

Diagnostic performance metrics at conceptual level

sensitivity and specificity ideas ROC curves and AUC thinking PPV / NPV and cut off selection concepts

From discovery signatures to candidate panels (idea level)

feature reduction and panel selection concepts overfitting awareness in biomarker models thinking about clinical validation studies

Session 4

Fee: Rs 18800

Mini Capstone: Biomarker Study & Panel Plan

Conceptual design for a simple clinical proteomics biomarker study

Theory + Practical (planning oriented)

From clinical question to cohort, samples and analysis outline

defining endpoints and comparison groups deciding discovery vs targeted phase sketching basic statistical and ROC evaluation steps

Mini capstone deliverables (design and narrative focused)

biomarker study design sheet outline candidate panel and metric table template short narrative linking panel to clinical use case

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Clinical Proteomics & Biomarker Discovery Training | Study Design, Panels & Interpretation

Clinical Proteomics & Biomarker Discovery — Hands-on