Clinical Proteomics — Biomarker Panels and Verification — Hands-on

Understand how quantitative proteomics concepts transition into clinical style biomarker panels and verification workflows. This module focuses on targeted assay thinking, panel design logic, verification and performance characteristics at a conceptual level, and how to summarize clinical proteomics results for decision support and regulated style reporting.

Clinical Proteomics — Biomarker Panels and Verification

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Session Index

Session 1 — Clinical Proteomics Foundations & Study Types Session 2 — Targeted Assay Concepts & Panel Design Session 3 — Verification, Reference Ranges & Performance Session 4 — Study Design, QC & Reporting in Clinical Proteomics

Session 1

Fee: Rs 8800

Clinical Proteomics Foundations & Study Types

From discovery proteomics to clinical style panels (conceptual)

discovery vs verification vs longitudinal thinking few marker panels vs broad profiling fit with existing clinical tests overview

Clinical proteomics study types at a glance

case control style designs prognostic and monitoring scenarios reference range and stability studies

Sample types and pre analytical variables conceptually

serum, plasma and other matrices collection, processing and storage ideas sources of variability and bias overview

Session 2

Fee: Rs 11800

Targeted Assay Concepts & Panel Design

Conceptual targeted LC–MS/MS assays for biomarkers

transition level measurement idea signature peptides and uniqueness internal standards and surrogates concepts

Selecting candidates and shaping a panel on paper

biological rationale and pathway coverage practical limits on panel size dynamic range and interference thinking

Assay layout, calibrators and controls at high level

calibration curve concepts QC sample tiers and placement run order and blocking ideas

Session 3

Fee: Rs 14800

Verification, Reference Ranges & Performance

Verification vs validation concepts for assays

analytical vs clinical performance views fit for intended use reasoning bridging from research to routine ideas

Key performance characteristics at a conceptual level

precision and accuracy overview limits of detection and quantitation ideas linearity, carryover and stability thinking

Reference intervals and clinical decision thresholds (conceptual)

reference interval construction logic ROC curves and cut off ideas sensitivity, specificity and predictive values

Session 4

Fee: Rs 18800

Study Design, QC & Reporting in Clinical Proteomics

Designing clinical proteomics verification studies on paper

theory plus planning worksheet

QC schemes for routine style proteomic panels

internal QC and external quality ideas run and batch level monitoring concepts trend and rule based thinking

Summarizing panels and results for clinical style reporting

clear tables of markers and units reference and decision thresholds noted transparent methods and limitations text

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Clinical Proteomics — Biomarker Panels and Verification Training | Targeted Assays & Performance Concepts

Clinical Proteomics — Biomarker Panels and Verification — Hands-on