Digital Twins & Patient Specific Systems Models — Hands-on

Learn how to design and implement digital twins and patient specific systems models that combine mechanistic models with omics, imaging and clinical data. This module focuses on model structuring, data linkage, calibration logic and scenario simulation so that you can build transparent and decision oriented digital twin prototypes for research and translational settings.

Digital Twins & Patient Specific Systems Models

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Session Index

Session 1 — Concepts, Architectures & Use Cases Session 2 — Structuring Patient Specific Mechanistic Models Session 3 — Data Integration, Updating & Monitoring Session 4 — Mini Capstone: Prototype Digital Twin Workflow

Session 1

Fee: Rs 8800

Concepts, Architectures & Use Cases

Digital twin ideas in engineering and life sciences

virtual replicas of patients or systems mechanistic plus data driven hybrids research vs clinical scenarios

Architectural patterns for biomedical digital twins

core mechanistic model layer data ingestion and pre processing layer interface, dashboard and API ideas

Scoping use cases and requirements for twins

therapy planning and what if scenarios monitoring disease trajectory trial enrichment and in silico arms

Session 2

Fee: Rs 11800

Structuring Patient Specific Mechanistic Models

Choosing model form and level of detail

ODE and compartment models PK PD and systems pharmacology structures coarse vs fine grained trade offs

Parameter maps for patient specific customisation

which parameters are patient specific linking to covariates and omics priors and physiological ranges

Digital twin ready model implementation practices

modular code and configuration files SBML and compatible formats unit testing and sanity checks

Session 3

Fee: Rs 14800

Data Integration, Updating & Monitoring

Data streams for twins and how to wire them

omics and biomarker panels imaging and device signals EHR and longitudinal labs

Updating models with new observations

refitting and recalibration logic filtering and state estimation ideas drift detection and alerting

Simulation dashboards and decision facing outputs

what if and scenario sliders risk bands and forecast plots documenting assumptions and limits

Session 4

Fee: Rs 18800

Mini Capstone: Prototype Digital Twin Workflow

Define a small digital twin scenario and data bundle

Theory + Practical

Instantiate a patient specific model and run scenarios

parameter customisation from data baseline and intervention simulations simple dashboard style outputs

Deliverables: model, scripts, configuration and short note

SBML or notebook model implementation config and example patient data files interpretation and future extension ideas

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Digital Twins & Patient Specific Systems Models Training | Mechanistic Twins & Simulation

Digital Twins & Patient Specific Systems Models — Hands-on