Glycan Biosynthesis Pathways & Glycosyltransferases — Hands-on

Learn how complex glycan structures are generated inside the cell. This module walks through N- and O-glycosylation pathways, glycosyltransferase families, compartmental organization and regulatory logic, preparing you to interpret glycan patterns, pathway defects and engineering strategies in research and biopharma settings.

Glycan Biosynthesis Pathways & Glycosyltransferases

Help Desk · WhatsApp

Session Index

Session 1 — Cellular Glycosylation Landscape Session 2 — N-Linked & O-Linked Glycosylation Pathways Session 3 — Glycosyltransferases, Glycosidases & Regulation Session 4 — Mini Capstone: Pathway Mapping & Defect Analysis

Session 1

Fee: Rs 8800

Cellular Glycosylation Landscape

Overview of glycosylation types and locations

N glycosylation O glycosylation GPI anchors & glycolipids

Organelle organization of glycan biosynthesis

ER vs Golgi roles cis to trans Golgi progression luminal vs cytosolic steps

Activated sugar donors and transport

nucleotide sugars (UDP, GDP, CMP) dolichol linked intermediates sugar nucleotide transporters

Session 2

Fee: Rs 11800

N-Linked & O-Linked Glycosylation Pathways

N linked glycosylation pathway

dolichol linked core assembly OST transfer to Asn sequon trimming and processing in ER

Golgi processing and branching of N glycans

high mannose to hybrid complex multiantennary structures fucosylation and sialylation

O linked glycosylation pathways

mucin type GalNAc initiation core 1, 2 and extended cores other O linkages overview

Session 3

Fee: Rs 14800

Glycosyltransferases, Glycosidases & Regulation

Glycosyltransferase families and specificities

GT family classification donor and acceptor recognition localization signals

Glycosidases and quality control

ER glucosidases and mannosidases Golgi trimming steps ERAD and folding cycles

Regulation and pathway rewiring

enzyme expression changes Golgi pH and trafficking nutrient and disease driven shifts

Session 4

Fee: Rs 18800

Mini Capstone: Pathway Mapping & Defect Analysis

Map full biosynthetic routes for key glycans

from activated sugars to final glycan structure

Explore congenital disorders of glycosylation at pathway level

enzyme defects predicted structural changes clinical phenotype connections

Deliverables and documentation

pathway diagrams enzyme and gene tables short PDF or HTML summary

PDF

Glycan Biosynthesis Pathways & Glycosyltransferases Training | N/O-Glycosylation & Enzymes

Glycan Biosynthesis Pathways & Glycosyltransferases — Hands-on