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Glycan Structure Chemistry — Linkages & Branching Training | Stereochemistry, Linkages, Branching

NTHRYS >> Services >> Academic Services >> Training Programs >> Bioinformatics Training >> Glycomics, Glycoproteomics & Glyco-Informatics >> Glycan Structure Chemistry — Linkages & Branching Training | Stereochemistry, Linkages, Branching

Glycan Structure Chemistry — Linkages & Branching — Hands-on

Deepen your understanding of glycan structure chemistry. This module connects monosaccharide stereochemistry, glycosidic linkages, branching patterns and conformational preferences to how glycans behave in real biological and analytical contexts, preparing you for advanced glycomics, glycoproteomics and glycoengineering work.

Glycan Structure Chemistry — Linkages & Branching
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Session 1
Fee: Rs 8800
Monosaccharide Stereochemistry & Conformation
  • Chirality, stereocenters and carbohydrate configuration
  • D and L series Fischer projections Haworth projections
  • Ring forms and anomeric effects
  • pyranose and furanose alpha and beta anomers mutarotation basics
  • Conformational preferences of hexoses
  • chair and boat forms axial vs equatorial steric and electronic effects
Session 2
Fee: Rs 11800
Glycosidic Linkages & Bond Geometry
  • Glycosidic bond formation concepts
  • anomeric position leaving groups overview activation strategies overview
  • Describing linkages in practice
  • alpha 1 4 and alpha 1 6 beta 1 3 and beta 1 4 sialyl and fucosyl linkages
  • Linkage effects on stability and recognition
  • enzyme specificity lectin binding susceptibility to hydrolysis
Session 3
Fee: Rs 14800
Branching Architectures & Structural Motifs
  • Branching patterns in N and O glycans
  • bi tri and tetra antennary core and outer arm modifications high mannose vs complex
  • Common structural motifs and epitopes
  • Lewis antigens overview sialyl Lewis patterns overview lactosamine repeats overview
  • 3D shape and flexibility of branched glycans
  • conformational ensembles steric crowding implications for binding surfaces
Session 4
Fee: Rs 18800
Mini Capstone: Structure to Function Stories
  • Rebuild real glycan structures from literature diagrams
  • from monosaccharide list to full branched structure
  • Relate linkages and branching to biological outcomes
  • clearance and half life receptor recognition disease associated changes
  • Deliverables and technical documentation
  • PDF or HTML mini report annotated linkage maps structure and metadata table


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