Immune System Simulation & In-Silico Trials — Hands-on

Gain an intuitive view of immune system simulation and in silico trial design. This module focuses on how conceptual immune models, virtual cohorts, dosing schedules and response readouts can be used to explore scenarios, compare strategies and support vaccine and immunotherapy development teams.

Immune System Simulation & In-Silico Trials

Help Desk · WhatsApp

Session Index

Session 1 — Immune System Simulation Foundations Session 2 — Virtual Cohorts, Dosing & Readouts Session 3 — Scenario Exploration & In-Silico Trials Session 4 — Trial Design Brief & Communication

Session 1

Fee: Rs 8800

Immune System Simulation Foundations

Why simulate the immune system for vaccines and biologics

exploring scenarios before or between experiments understanding kinetics of responses conceptually support for dose, schedule and population choices

Conceptual blocks in immune system models (orientation)

innate and adaptive compartments overview antigen, APC, T cells and B cells in simple diagrams cytokines and signals in a coarse grained way

Model types in plain language (no equations needed here)

compartment style models orientation rule based and agent style narratives how assumptions drive model behaviour

Session 2

Fee: Rs 11800

Virtual Cohorts, Dosing & Readouts

Virtual individuals and variability (conceptual cohort)

parameters that differ between virtual subjects heterogeneity in immune strength and kinetics mapping to real world population ideas

Dosing schedules and administration patterns in models

single dose, prime boost and multi dose regimens intervals, delays and missed doses (orientation) link to real trial protocol language

Model outputs and immune readouts (conceptual)

antibody titres and T cell response curves response rate style summaries how outputs align with clinical endpoints

Session 3

Fee: Rs 14800

Scenario Exploration & In-Silico Trials

From single subject simulations to virtual trials (conceptual)

running many virtual subjects with variability simple arms such as control versus candidate aggregating outcomes as trial style summaries

Sensitivity and uncertainty in plain language

which assumptions drive outcomes the most ranges and confidence style views (conceptual) communicating what is robust versus fragile

Use cases for design decision support (conceptual stories)

comparing alternative schedules or doses exploring responder subgroups at high level aligning with study design discussions

Session 4

Fee: Rs 18800

Trial Design Brief & Communication

Framing questions that simulation can help answer

clarifying decision points for teams defining simple scenarios and comparators noting constraints and assumptions up front

Packaging simulation insights for non modelers (conceptual)

plots and tables that tell a clear story simple language for uncertainty and caveats highlighting what may change design choices

Handoff to clinical, regulatory and systems teams (conceptual)

link to protocol design and power discussions placing results alongside empirical data alignment with host pathogen and systems modules

PDF

Immune System Simulation & In-Silico Trials Training | Virtual Cohorts & Design Scenarios

Immune System Simulation & In-Silico Trials — Hands-on