Integrative Multi-Omics (G/T/P/M) — Hands-on

Gain expertise in integrating Genomics, Transcriptomics, Proteomics, and Metabolomics (G/T/P/M) with rigorous QC, batch correction, data fusion, pathway and network biology—fully reproducible, hands-on.

Integrative Multi-Omics (G/T/P/M)

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Session Index

Session 1 — Data QC, Scaling & Harmonization Session 2 — Cross-Omics Integration (CCA/PLS/DIABLO) Session 3 — Networks, Pathways & Causal Views Session 4 — Mini Capstone: Translational Multi-Omics

Session 1

Fee: Rs 6300

Data QC, Scaling & Harmonization

Omics-specific QC (counts/intensity/peak areas) & missing data

Theory

Normalization & transformation strategies across omes

TMM/RLE VST/logCPM Quantile Pareto/Autoscale

Batch effects & drift correction

ComBat removeBatchEffect LOESS

Session 2

Fee: Rs 8400

Cross-Omics Integration (CCA/PLS/DIABLO)

Correlation-based fusion & dimensionality reduction

CCA PLS/PLS-DA sPLS

Multi-block frameworks for supervised integration

mixOmics DIABLO Sparse models Cross-validation

Unsupervised latent factor models for multi-omics

MOFA/MOFA+ NMF

Session 3

Fee: Rs 11200

Networks, Pathways & Causal Views

Multi-layer networks & cross-modal communities

Cytoscape igraph STRING

Pathway overlays across omes & concordance scoring

KEGG/Reactome GSEA/ORA

Causal graphs & mediation (omics→phenotype)

bnlearn DoWhy

Session 4

Fee: Rs 14000

Mini Capstone: Translational Multi-Omics

Design an end-to-end multi-omics pipeline with provenance

Theory

Automate ingest→integrate→analyze→report workflow

Snakemake Conda/Mamba Quarto/JupyterLab

Deliver dashboards & clinical interpretation summaries

pandas ggplot2 plotly

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Integrative Multi-Omics (G/T/P/M) Training | mixOmics DIABLO, MOFA, Networks & Pathways

Integrative Multi-Omics (G/T/P/M) — Hands-on