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Multi Scale Models Cells Tissues and Organs Training | From Cellular to Organ Scale Modeling

NTHRYS >> Services >> Academic Services >> Training Programs >> Bioinformatics Training >> Systems Biology, Network Modeling & Pathway Dynamics >> Multi Scale Models Cells Tissues and Organs Training | From Cellular to Organ Scale Modeling

Multi Scale Models Cells Tissues and Organs — Hands-on

Learn how to construct and analyze multi scale models that connect cellular dynamics to tissue level behavior and organ scale physiology. This module covers conceptual foundations, common coupling strategies, numerical considerations and practical workflows that bridge in vitro, in vivo and in silico views.

Multi Scale Models — Cells, Tissues & Organs
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Session 1
Fee: Rs 8800
Foundations of Multi Scale Modeling
  • Why multi scale models for biology and medicine
  • molecular to organ scale thinking top down vs bottom up views example use cases
  • Types of models across scales
  • ODE and PDE based models agent based and cellular automata lumped vs distributed descriptions
  • Concepts of scale separation and coupling
  • time scale separation spatial resolution choices information flow between levels
Session 2
Fee: Rs 11800
Coupling Cellular & Tissue Level Models
  • From single cell dynamics to tissue behavior
  • cell state models and fate decisions contact, signaling and mechanics emergent tissue patterns
  • Coupling strategies and numerical workflow
  • operator splitting ideas co-simulation approaches data exchange between solvers
  • Examples in development, cancer and regeneration
  • patterning and morphogenesis tumor growth in tissue context wound healing sketches
Session 3
Fee: Rs 14800
Organ Scale & Hybrid Approaches
  • Organ level and whole body models
  • lumped physiology models compartment and flow models linking to PK PD style models
  • Hybrid and surrogate modeling ideas
  • mechanistic plus data driven reduced order and metamodels tradeoffs between speed and detail
  • Multi scale calibration and validation challenges
  • data at different scales consistency across levels avoid overfitting at one scale
Session 4
Fee: Rs 18800
Mini Capstone: Multi Scale Workflow
  • Pick a simple multi scale question and define levels to model
  • Theory plus guided practical
  • Implement a small two scale prototype and explore scenarios
  • simple cell and tissue coupling parameter or input scans basic robustness checks
  • Deliverables: notebook, schematic and short summary
  • Python or R notebook diagram of scales and couplings PDF or HTML summary


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