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Network Inference & Microbial Ecology Models Training | Co-Occurrence & Ecological Networks

NTHRYS >> Services >> Academic Services >> Training Programs >> Bioinformatics Training >> Microbiome, Metagenomics & Microbial Systems Biology >> Network Inference & Microbial Ecology Models Training | Co-Occurrence & Ecological Networks

Network Inference & Microbial Ecology Models — Hands-on

Learn how to move from microbiome abundance tables to interpretable ecological networks. You will explore association frameworks, build sparse co-occurrence networks, interpret topology and keystone taxa, and summarize microbial ecology models in a way that supports hypothesis generation, intervention design and downstream simulation work.

Network Inference and Microbial Ecology Models
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Session 1
Fee: Rs 8800
Microbial Ecology Concepts & Network Thinking
  • Microbial ecology interactions and community structure
  • competition, mutualism and commensalism niche vs neutral perspectives stability, resilience and regime shifts
  • Why use networks for microbiome data
  • moving beyond univariate associations capturing multi taxon interaction patterns bridging to dynamical models and simulations
  • Limitations of naive co occurrence and correlation views
  • compositionality and spurious correlations indirect vs direct associations mindset confounding by environment and host factors
Session 2
Fee: Rs 11800
From Abundance Tables to Association Matrices
  • Preparing microbiome feature tables for network inference
  • choice of taxonomic or functional resolution prevalence and abundance filtering ideas transformations and scale considerations
  • Association and correlation frameworks for microbiomes
  • Spearman and rank based thinking compositionality aware ideas (log ratios, proportionality) sparsity and zero inflation awareness
  • Sparsity oriented and graphical model perspectives
  • partial correlation and conditional dependence graphical model style inference concepts controlling density and multiple testing
Session 3
Fee: Rs 14800
Network Topology, Keystone Taxa & Ecology Models
  • From association matrices to graphs and layouts
  • edge filtering and thresholding ideas signed vs unsigned networks visualization and layout choices
  • Network topology and keystone taxon concepts
  • degree, centrality and hubs modules, communities and guilds candidate keystone taxa thinking
  • Ecological interpretation and links to dynamical models
  • network robustness and perturbation ideas hypothesis generation for interventions network views as inputs to simulation models
Session 4
Fee: Rs 18800
Mini Capstone: Microbial Ecology Network Report
  • End to end network inference on a cohort
  • Theory plus guided practical
  • Interpreting modules, hubs and keystone candidates with metadata
  • linking network features to phenotypes clinical, environmental and industrial examples caveats on causality and over interpretation
  • Deliverables: adjacency tables, network plots & methods block
  • association and adjacency matrices network and module visualization panels reusable network analysis methods text


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