Network Theory — Graph Construction & Topological Measures — Hands-on

Gain a practical, systems-level understanding of network theory for biology. This module walks you from graph fundamentals and network construction from omics data to computing and interpreting topological measures, centralities, communities, and robustness indicators for real biological networks.

Network Theory — Graph Construction & Topological Measures

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Session Index

Session 1 — Graph Basics & Network Types Session 2 — Graph Construction from Biological Data Session 3 — Topological Measures & Centralities Session 4 — Mini Capstone: Analyze a Biological Network

Session 1

Fee: Rs 8800

Graph Basics & Network Types

Graph theory foundations for biology

nodes, edges, degree paths, walks, cycles directed vs undirected

Types of biological networks

PPI & co-expression networks metabolic & pathway graphs gene regulatory networks

Representations & data structures

adjacency matrices & lists edge tables weighted & signed edges

Session 2

Fee: Rs 11800

Graph Construction from Biological Data

Building networks from omics & interaction data

co-expression thresholds correlation & mutual information PPI & STRING integration

Cleaning, filtering & weighting edges

confidence scores edge pruning & sparsity multi-layer networks preview

Implementation toolkit for graph building

Python / networkx R / igraph Cytoscape I/O (SIF, GraphML)

Session 3

Fee: Rs 14800

Topological Measures & Centralities

Global network topology metrics

degree distribution clustering coefficient path length & small-world

Node centralities & hubs/bottlenecks

degree & betweenness closeness & eigenvector PageRank & influence scores

Communities, modules & enrichment hooks

Louvain / Leiden clustering module detection in Cytoscape link to GO/pathway enrichment

Session 4

Fee: Rs 18800

Mini Capstone: Analyze a Biological Network

Construct and analyze a PPI or pathway network

Theory + Practical

Compute key metrics & identify hubs/modules

centrality ranking tables community visualization biological interpretation

Deliverables: scripts, network files & summary

Python/R notebook GraphML / SIF / CSV PDF/HTML network report

PDF

Network Theory, Graph Construction & Topological Measures Training | Centrality, Communities, Topology

Network Theory — Graph Construction & Topological Measures — Hands-on