Onco-Immunology Signatures & Biomarker Panels — Hands-on

Gain a conceptual understanding of onco immunology signatures and biomarker panels. This module explains tumour immune microenvironment readouts, composite signature ideas and panel level thinking so you can frame immunotherapy, trial and translational oncology questions in biomarker language without needing to write code.

Onco-Immunology Signatures & Biomarker Panels

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Session Index

Session 1 — Tumour–Immune Microenvironment Foundations Session 2 — Onco-Immunology Signatures & Scores Session 3 — Biomarker Panels for Immunotherapy & Trials Session 4 — Design Brief: Onco-Immunology Biomarker Plan

Session 1

Fee: Rs 8800

Tumour–Immune Microenvironment Foundations

Tumour, immune and stromal compartments in plain language

cancer cells, infiltrating immune cells and stroma overview inflamed, immune excluded and cold tumours as concepts how microenvironment patterns relate to therapy response ideas

Common readouts used to describe the tumour immune contexture

T cell, myeloid and stromal infiltration notions checkpoint and activation marker expression ideas simple sketches of inflamed and suppressive scenarios

Data types feeding onco immunology signatures (orientation only)

bulk gene expression and protein staining concepts circulating markers and peripheral blood profiles links to repertoire, neoantigen and immunopeptidomics modules

Session 2

Fee: Rs 11800

Onco-Immunology Signatures & Scores

What a signature or score means in this context (conceptual)

multi marker patterns summarised into a single number examples such as cytolytic, interferon like and inflamed style scores separation between prognostic and predictive signatures ideas

Inputs that typically feed onco immunology signatures (orientation)

expression levels of immune genes and pathways simple cell proportion or enrichment style concepts combining immune, tumour and genomic context conceptually

Interpreting signature values in a trial or cohort narrative

high versus low categories as simple strata associations with response, survival or toxicity outcomes cautions around cutoffs, context and generalisability

Session 3

Fee: Rs 14800

Biomarker Panels for Immunotherapy & Trials

Thinking in terms of panels rather than single markers (conceptual)

combinations of tissue, blood and genomic markers balancing feasibility, cost and information content panels for selection, monitoring and mechanism exploration

Examples of onco immunology biomarker dimensions (high level)

checkpoint and immune activation markers in tissue simple circulating immune and inflammatory readouts genomic context such as mutation and antigenicity features

Longitudinal and response monitoring concepts for panels

baseline versus on treatment biomarker views patterns in responders and non responders as stories early change markers and durability signals in principle

Session 4

Fee: Rs 18800

Design Brief: Onco-Immunology Biomarker Plan

Framing study and therapy questions in biomarker terms

what decision the biomarker information should support choosing core and optional markers conceptually noting timing and sample type for each readout

Sketching a practical biomarker panel for a trial or cohort (conceptual)

simple table with markers, rationale and logistics notes alignment with available assays and sample flows integration with existing signatures and scores

Communicating biomarker plans and limitations clearly to teams

slide ready summary figures and timelines explicit assumptions, risks and contingency notes handoff to clinical, lab and regulatory colleagues

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Onco-Immunology Signatures & Biomarker Panels Training | Tumour–Immune Biomarkers for Immunotherapy

Onco-Immunology Signatures & Biomarker Panels — Hands-on