PGx in Oncology — Targeted Therapies and Toxicity — Hands-on

Connect pharmacogenomics with oncology decision making. This module focuses on germline PGx markers for chemotherapy and targeted agents, linking variant driven toxicity risk, dose individualization and supportive care planning through practical, case based exercises.

PGx in Oncology — Targeted Therapies and Toxicity

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Session Index

Session 1 — Foundations of Oncology PGx & Pathways Session 2 — Chemotherapy Toxicity & Germline Markers Session 3 — Targeted Therapies, Supportive Care & PGx Session 4 — Mini Capstone: Oncology PGx Case Board

Session 1

Fee: Rs 8800

Foundations of Oncology PGx & Pathways

Oncology biomarkers vs germline pharmacogenomics

somatic targets vs germline PGx efficacy vs toxicity focus lines of therapy context

Key ADME pathways relevant to cancer regimens

fluoropyrimidine metabolism thiopurine pathways UGT mediated clearance

Where PGx adds value in oncology workflows

pre treatment risk assessment dose selection and escalation supportive care planning

Session 2

Fee: Rs 11800

Chemotherapy Toxicity & Germline Markers

Fluoropyrimidines and DPYD related toxicity risk

reduced function alleles conceptually dose reduction logic monitoring for early toxicity signs

Thiopurines and TPMT NUDT15 based risk categories

myelosuppression risk patterns initial dose choices role of serial counts and TDM

Irinotecan and UGT mediated toxicity profiles

neutropenia and diarrhea risk high risk genotypes conceptually practical dose modification examples

Session 3

Fee: Rs 14800

Targeted Therapies, Supportive Care & PGx

PGx around selected targeted and endocrine therapies

metabolic pathways for oral agents transporters and exposure co prescribed inhibitors conceptually

Supportive care medicines with PGx relevance in oncology

antiemetics and analgesics psychiatric and neuropathic agents anticoagulants and antiplatelets

Integrating PGx into multidisciplinary tumor board thinking

summarizing PGx in case notes explaining risk to team members aligning with overall treatment goals

Session 4

Fee: Rs 18800

Mini Capstone: Oncology PGx Case Board

Worked oncology case with PGx and regimen choices

summarize diagnosis and plan identify relevant germline markers map to toxicity risk and dosing

PGx in Oncology — Targeted Therapies & Toxicity Training | Germline Risk, Dosing & Supportive Care

PGx in Oncology — Targeted Therapies and Toxicity — Hands-on