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Pharmacogenomics & Drug–Gene Interaction Analytics | CPIC/DPWG, Star Alleles, CDS

NTHRYS >> Services >> Academic Services >> Training Programs >> Bioinformatics Training >> Clinical & Translational Bioinformatics / Precision Medicine >> Pharmacogenomics & Drug–Gene Interaction Analytics | CPIC/DPWG, Star Alleles, CDS

Pharmacogenomics & Drug–Gene Interaction Analytics — Hands-on

Translate genomic variation into safer, effective prescribing. This module builds end-to-end pharmacogenomics (PGx) capability: star-allele calling (including complex loci) , guideline-driven interpretation (CPIC/DPWG) , structured reporting, and integration of PGx knowledge into clinical decision support (CDS) within EHR workflows.

Pharmacogenomics & Drug–Gene Interaction Analytics
Help Desk · WhatsApp
Session 1
Fee: Rs 15320
PGx Foundations & Guidelines
  • ADME pharmacogenes & phenotypes
    • CYPs, TPMT/NUDT15, DPYD UGT/SLCO1B1 metabolizer status
  • Guidelines & resources
    • CPIC / DPWG PharmGKB levels drug labels (high-level)
  • Nomenclature & translation
    • HGVS & star alleles activity score → phenotype ethnic variability
Session 2
Fee: Rs 19520
Star-Allele Calling & Annotation
  • Data & tools
    • genotype arrays / NGS PharmCAT annotation pipelines
  • Complex loci (CYP2D6 etc.)
    • CNVs/dups & hybrids Aldy / Stargazer QC & confirmation
  • Phenotype translation
    • activity scores IM/PM/UM calls edge cases & VUS
Session 3
Fee: Rs 23720
Drug–Gene Interaction Analytics & CDS
  • Dose adjustments & alternatives
    • CPIC/DPWG rules actionability tiers label considerations
  • DDGIs & co-medications
    • drug–drug–gene logic inhibitors/inducers risk flags
  • EHR integration & CDS hooks
    • FHIR resources alerts & summaries provenance & audits
Session 4
Fee: Rs 29320
Reporting, Implementation & QA
  • Report templates & language
    • phenotype & recommendation limitations citations
  • Implementation & governance
    • consent & ethics population screening updates & reanalysis
  • Quality & validation
    • LoD & proficiency change control audit trails


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