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Systems Biology Foundations & Standards Training | SBML, SBGN & Reproducible Pathway Modeling

NTHRYS >> Services >> Academic Services >> Training Programs >> Bioinformatics Training >> Systems Biology, Network Medicine & Pathway Modeling >> Systems Biology Foundations & Standards Training | SBML, SBGN & Reproducible Pathway Modeling

Systems Biology Foundations & Standards — Hands-on

Build a rigorous foundation in systems biology and community standards for executable models. This module connects conceptual modeling paradigms with SBML, SBGN and COMBINE Archives so that your pathway and network models are reusable, shareable and compliant with FAIR principles.

Systems Biology Foundations & Standards
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Session 1
Fee: Rs 8800
Systems Biology Concepts & Modeling Paradigms
  • From pathways to systems level behavior
  • feedback and feedforward loops homeostasis and oscillations emergent properties
  • Modeling formalisms and assumptions
  • ODE and deterministic models stochastic and Gillespie view logical and constraint based
  • States, parameters and observables
  • species and compartments rate laws and units linking data to models
Session 2
Fee: Rs 11800
SBML, SBGN & Model Encodings
  • SBML structure and common patterns
  • species and reactions parameters and rules events and initialisation
  • SBGN diagrams and pathway communication
  • process description maps entity relationship views activity flow schematics
  • FAIR friendly metadata and archives
  • annotations and ontologies COMBINE Archive basics MIRIAM style reporting
Session 3
Fee: Rs 14800
Repositories, Tools & Workflows
  • Model repositories and discovery
  • BioModels and CellML JWS Online and VCell community curated models
  • Simulation and analysis toolchain
  • COPASI and tellurium Python based workflows parameter scans and basic sensitivity
  • Reproducible configurations
  • environment capture version control of models notebooks and reports
Session 4
Fee: Rs 18800
Mini Capstone: Pathway to Executable Model
  • From pathway diagram to SBML and SBGN
  • Theory + Practical
  • Basic simulations and scenario analysis
  • time course runs parameter changes qualitative sensitivity
  • Packaging and documentation
  • COMBINE Archive metadata and README FAIR oriented deliverables


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