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Nano Biotechnology Internship Topics

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Nano Biotechnology Internships with Accommodation

Choose an internship topic, then explore accommodation-enabled internship options at active NTHRYS branch locations in India.

Showing 13–24 of 35 internship topics
In Vitro Transfection and Cell Uptake Mechanisms
Interns will conduct cell culture studies to evaluate transfection efficiency of chitosan nanoparticle-gene complexes in various cell lines using fluorescent-tagged particles and flow cytometry analysis. They will investigate cellular uptake pathways, including endocytosis mechanisms and intracellular trafficking patterns.
Chitosan Nanoparticle Gene Delivery ResearchView internship →
Biocompatibility and Cytotoxicity Assessment
Interns will perform standardized cytotoxicity assays (MTT, LDH release) and biocompatibility studies on chitosan nanoparticles across different cell types to determine safe concentration ranges. This work includes evaluating the impact of particle size, surface modifications, and polymer molecular weight on cell viability and inflammatory responses.
Chitosan Nanoparticle Gene Delivery ResearchView internship →
Surface Modification and Targeting Ligand Conjugation
Interns will explore chemical functionalization of chitosan nanoparticles with targeting ligands (antibodies, peptides, folate) and fluorescent markers using conjugation chemistry techniques. They will characterize modified particles and assess how surface modifications affect gene delivery efficiency and cellular specificity in targeted delivery applications.
Chitosan Nanoparticle Gene Delivery ResearchView internship →
Albumin Nanoparticle Synthesis and Characterization
Interns will work on developing and optimizing methods for synthesizing albumin nanoparticles using techniques such as desolvation, coacervation, and self-assembly. They will characterize the particles using DLS, TEM, SEM, and zeta potential analysis to ensure uniform size distribution and stability for cancer targeting applications.
Albumin Nanoparticle Cancer TargetingView internship →
Drug Loading and Release Kinetics
Interns will investigate optimal methods for loading chemotherapeutic drugs (such as paclitaxel or doxorubicin) onto albumin nanoparticles and study their release profiles under physiological conditions. This includes performing in vitro release studies and analyzing drug-nanoparticle interactions using HPLC and UV-Vis spectroscopy.
Albumin Nanoparticle Cancer TargetingView internship →
Targeting Ligand Conjugation and Surface Modification
Interns will design and execute protocols for conjugating targeting ligands (antibodies, peptides, or folate receptors) to albumin nanoparticle surfaces using chemical crosslinking techniques. They will validate successful conjugation and assess targeting specificity through analytical methods like gel electrophoresis and mass spectrometry.
Albumin Nanoparticle Cancer TargetingView internship →
In Vitro Cancer Cell Targeting and Cytotoxicity Studies
Interns will conduct cell-based experiments to evaluate the targeting efficiency and cellular uptake of drug-loaded albumin nanoparticles in various cancer cell lines using fluorescence microscopy and flow cytometry. They will also assess cytotoxic effects compared to free drug controls through MTT assays and apoptosis studies.
Albumin Nanoparticle Cancer TargetingView internship →
Biocompatibility and Pharmacokinetic Assessment
Interns will evaluate the biocompatibility of albumin nanoparticles through hemolysis assays and protein adsorption studies, and conduct preliminary pharmacokinetic analyses using animal models or ex vivo tissue studies. This includes assessing biodistribution, circulation time, and potential immunogenicity of the nanoparticles.
Albumin Nanoparticle Cancer TargetingView internship →
Gold Nanoparticle Synthesis and Characterization for PAI
Interns will synthesize gold nanoparticles of varying sizes and shapes using chemical reduction methods, then characterize their optical and photothermal properties using UV-Vis spectroscopy and transmission electron microscopy. This work focuses on optimizing nanoparticle parameters to enhance photoacoustic signal generation for biomedical imaging applications.
Nanoparticle Photoacoustic Imaging ContrastView internship →
Surface Functionalization of Nanoparticles for Biomarker Targeting
Interns will design and execute surface modification protocols to conjugate targeting ligands, antibodies, or peptides onto nanoparticle surfaces for selective binding to disease biomarkers. The work includes validation of successful conjugation through various analytical techniques and assessment of binding specificity in biological models.
Nanoparticle Photoacoustic Imaging ContrastView internship →
Photoacoustic Signal Optimization and Detection Methods
Interns will investigate how nanoparticle composition, concentration, and laser wavelength parameters affect photoacoustic signal intensity and quality. This includes hands-on work with PAI instrumentation, signal processing algorithms, and optimization of imaging protocols to maximize contrast and resolution in tissue phantoms and biological samples.
Nanoparticle Photoacoustic Imaging ContrastView internship →
In Vitro Biocompatibility and Cellular Uptake Studies
Interns will evaluate the cytotoxicity, cellular internalization pathways, and intracellular localization of functionalized nanoparticles using cell culture models, flow cytometry, and fluorescence microscopy. This research assesses the safety profile and efficacy of nanoparticles as contrast agents for diagnostic applications.
Nanoparticle Photoacoustic Imaging ContrastView internship →
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