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Industrial Microbiology Project Topics

Browse all focused areas across all project categories under this field.

Showing 97–108 of 305 project topics
Bacillus pumilus Production
A spore-former with limited human data, used in agricultural and feed contexts. Production follows standard aerobic Bacillus protocols. Projects assess sporulation kinetics and formulation stability.
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Bacillus indicus Production
A carotenoid-producing spore-former giving pigmented colonies, explored as an antioxidant-delivering probiotic. Production can target carotenoid content alongside spore yield. Projects cover pigment quantification and dual-function product design.
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Priestia megaterium Production
Formerly Bacillus megaterium, a large-celled species used industrially for vitamin B12 and enzyme production. Production is aerobic with high biomass potential. Projects study B12 biosynthesis and downstream recovery.
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Saccharomyces cerevisiae var. boulardii Production
The only yeast with substantial clinical evidence, used for antibiotic-associated and travellers' diarrhoea and inherently resistant to antibacterials. Production is aerobic yeast fermentation on molasses with fluid-bed or spray drying. Projects cover aerobic scale-up, drying survival and co-administration with antibiotic therapy.
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Saccharomyces cerevisiae Production
Baker's and brewer's yeast, produced at the largest scale of any probiotic-adjacent organism. Production uses fed-batch molasses fermentation with tight sugar feed control to avoid the Crabtree effect. Projects address feed profiling, biomass yield and comparison with the boulardii variant.
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Kluyveromyces marxianus Production
A lactose-fermenting yeast used with bifidobacteria in dairy applications. Production can valorise cheese whey as a substrate, turning a waste stream into biomass. Projects cover whey utilisation, thermotolerant fermentation and dairy co-culture design.
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Debaryomyces hansenii Production
A halotolerant yeast forming part of cheese surface flora and fermented foods. Production exploits salt tolerance to reduce contamination risk. Projects study osmotolerance and surface-ripening culture performance.
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Escherichia coli Nissle 1917 Production
A non-pathogenic strain used for ulcerative colitis, defined at strain rather than species level and a leading chassis for engineered live biotherapeutics. Production is standard aerobic E. coli fermentation with rigorous strain identity and endotoxin control. Projects cover identity verification, enteric coating and genetic stability monitoring.
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Clostridium butyricum Production
A butyrate-producing spore-former widely used in Japan, combining spore stability with short-chain fatty acid delivery. Production requires strict anaerobiosis followed by sporulation and spore recovery. Projects cover anaerobic bioreactor design, butyrate quantification and spore formulation.
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Akkermansia muciniphila Production
A mucin-degrading next-generation organism whose pasteurised form was authorised as an EU novel food in 2021. Production is technically demanding, requiring anaerobic cultivation on mucin or synthetic substitutes. Projects address mucin-free media development, anaerobic scale-up and pasteurisation validation.
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Faecalibacterium prausnitzii Production
A major butyrate producer and leading next-generation candidate for IBD, but extremely oxygen-sensitive. Production requires specialised anaerobic equipment and antioxidant-protected formulation. Projects cover oxygen-scavenging media, cryoprotection and viability assay development.
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Anaerobutyricum hallii Production
Formerly Eubacterium hallii, reclassified in 2019 and studied for metabolic health through butyrate and propionate production. Production demands strict anaerobiosis and defined gut-mimicking media. Projects examine cross-feeding with primary degraders and scale-up feasibility.
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