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Molecular Biology Internship Topics

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Molecular Biology Internships with Accommodation

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Showing 145–155 of 155 internship topics
Apoptosis Evasion Mechanisms in Disease Models
Interns will investigate how cancer cells and pathogens evade programmed cell death through anti-apoptotic protein overexpression and pathway inhibition. They will use gene expression profiling, CRISPR-based knockdown studies, and cell viability assays to identify therapeutic targets for apoptosis restoration.
Apoptosis Programmed Cell Death PathwaysView internship →
SNP Genotyping and Allele Frequency Analysis
Interns will learn to identify and catalog single nucleotide polymorphisms (SNPs) across diverse population samples using molecular techniques and bioinformatics tools. They will analyze allele frequencies, calculate Hardy-Weinberg equilibrium, and interpret population-level genetic variation patterns.
Genomic Polymorphism Population Genetics StudyView internship →
Population Stratification and Ancestry Inference
Interns will work with genomic datasets to detect population structure using principal component analysis (PCA) and ancestry informative markers. They will learn to assess genetic ancestry composition in mixed populations and understand how population stratification affects association studies.
Genomic Polymorphism Population Genetics StudyView internship →
Linkage Disequilibrium Mapping and Haplotype Analysis
Interns will investigate linkage disequilibrium (LD) patterns within and across populations using genome-wide association data. They will construct haplotype blocks, perform haplotype frequency estimation, and examine how LD varies across different ethnic populations.
Genomic Polymorphism Population Genetics StudyView internship →
Genome-Wide Association Study (GWAS) Data Analysis
Interns will process and analyze GWAS datasets to identify genetic variants associated with phenotypic traits in different populations. They will perform quality control, statistical testing, and interpretation of significant loci while considering population-specific effects.
Genomic Polymorphism Population Genetics StudyView internship →
Evolutionary Population Genetics and Selection Signatures
Interns will examine genomic evidence of natural selection, population bottlenecks, and demographic history using polymorphism data across populations. They will calculate Fst values, Tajima's D, and other population genetic statistics to understand evolutionary processes shaping genetic diversity.
Genomic Polymorphism Population Genetics StudyView internship →
Virtual Screening of Small Molecule Libraries Against Target Proteins
Interns will learn to perform computational screening of large compound databases against disease-relevant protein targets using molecular docking software. They will analyze binding affinities, predict drug-like properties, and identify promising lead compounds for further experimental validation.
Molecular Docking Drug Candidate ScreeningView internship →
Structure-Based Drug Design and Ligand Optimization
Interns will work on refining hit compounds through iterative docking studies, exploring chemical modifications to improve binding interactions and selectivity. They will learn to interpret docking poses, predict ADMET properties, and design derivatives with enhanced pharmacological profiles.
Molecular Docking Drug Candidate ScreeningView internship →
Protein-Ligand Interaction Analysis and Molecular Modeling
Interns will conduct detailed analyses of protein-drug interactions using docking software and molecular dynamics simulations. They will characterize binding modes, identify critical residues for binding, and create visualizations to support structure-activity relationship (SAR) studies.
Molecular Docking Drug Candidate ScreeningView internship →
High-Throughput Docking Pipeline Development and Validation
Interns will assist in setting up and optimizing automated docking workflows for screening multiple targets and compounds. They will perform validation studies against known actives/inactives and troubleshoot computational pipelines to ensure accuracy and efficiency.
Molecular Docking Drug Candidate ScreeningView internship →
Polypharmacology Prediction and Off-Target Analysis
Interns will perform cross-docking studies to predict how drug candidates interact with multiple biological targets beyond the primary target. They will assess potential off-target effects and toxicity risks using computational approaches to support safer drug candidate selection.
Molecular Docking Drug Candidate ScreeningView internship →
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