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Molecular Biology Internship Topics

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Molecular Biology Internships with Accommodation

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Showing 109–120 of 155 internship topics
Transposable Element Identification and Mapping
Interns will identify, classify, and map transposable elements and insertion sequences within bacterial genomes that facilitate horizontal gene transfer. They will develop databases and create visual representations of transposon distribution patterns and analyze their role in genome rearrangement and phenotypic variation.
Horizontal Gene Transfer Microbial StudyView internship →
Antibiotic Resistance Gene Dissemination Networks
Interns will trace the acquisition and spread of antibiotic resistance genes across clinically relevant bacterial pathogens using genomic and epidemiological data. Students will construct gene transfer networks, identify mobile genetic elements carrying resistance markers, and predict potential risk factors for resistance gene distribution in hospital and community settings.
Horizontal Gene Transfer Microbial StudyView internship →
Phosphorylation Mapping and Kinase Substrate Identification
Interns will learn to identify and map phosphorylation sites on target proteins using mass spectrometry and computational tools. They will work on characterizing kinase-substrate interactions and understanding how phosphorylation affects protein function and cellular signaling pathways.
Protein Post-Translational Modification StudyView internship →
Ubiquitination and Protein Degradation Pathways
Interns will study ubiquitin conjugation mechanisms and their role in protein degradation through the proteasomal and autophagy pathways. They will perform experiments to identify ubiquitination sites, characterize E3 ligase specificity, and analyze how modifications regulate protein stability and localization.
Protein Post-Translational Modification StudyView internship →
Glycosylation Analysis and Protein Quality Control
Interns will investigate N-linked and O-linked glycosylation patterns on proteins and their effects on protein folding, stability, and immune recognition. They will utilize lectin-based assays, chromatography techniques, and structural analysis to understand how glycosylation influences protein function in disease and development.
Protein Post-Translational Modification StudyView internship →
Acetylation and Histone Modification in Gene Regulation
Interns will examine lysine acetylation on histone and non-histone proteins and their critical roles in transcriptional regulation and chromatin remodeling. They will perform chromatin immunoprecipitation assays and analyze how acetyltransferases and deacetylases control epigenetic gene expression.
Protein Post-Translational Modification StudyView internship →
SUMOylation and Protein-Protein Interaction Networks
Interns will study small ubiquitin-like modifier (SUMO) conjugation and its effects on protein localization, stability, and interactions. They will use yeast two-hybrid assays, immunofluorescence, and co-immunoprecipitation to map SUMO substrates and understand how this modification regulates cellular processes and disease mechanisms.
Protein Post-Translational Modification StudyView internship →
Beta-Lactamase Enzyme Characterization and Inhibitor Screening
Interns will isolate and characterize beta-lactamase enzymes from antibiotic-resistant bacterial strains, perform enzyme kinetics assays, and screen potential inhibitor compounds. This work involves protein purification, substrate specificity analysis, and structure-function relationship studies to identify novel therapeutic targets.
Antibiotic Resistance Mechanism InvestigationView internship →
Horizontal Gene Transfer Pathway Analysis
Interns will investigate the mechanisms of antibiotic resistance gene transfer between bacterial species through conjugation, transformation, and transduction experiments. They will analyze plasmid sequences, identify mobile genetic elements, and determine transfer frequencies under various environmental conditions.
Antibiotic Resistance Mechanism InvestigationView internship →
Efflux Pump Function and Expression Regulation
Interns will study bacterial efflux pump systems responsible for antibiotic extrusion using molecular and biochemical techniques including RT-qPCR, Western blotting, and efflux assays. Research will focus on understanding upregulation mechanisms and evaluating efflux pump inhibitors as adjunct therapies.
Antibiotic Resistance Mechanism InvestigationView internship →
Whole Genome Sequencing and Comparative Genomics of Resistant Strains
Interns will perform Next-Generation Sequencing on antibiotic-resistant bacterial isolates and conduct bioinformatic analysis to identify resistance-conferring mutations and genetic markers. They will compare genomes of susceptible and resistant strains to map evolutionary pathways of resistance development.
Antibiotic Resistance Mechanism InvestigationView internship →
Phenotypic and Genotypic Resistance Pattern Profiling
Interns will conduct antimicrobial susceptibility testing using broth microdilution and disk diffusion methods, correlate phenotypic resistance patterns with underlying genetic determinants, and maintain a resistance database. This includes identifying emerging resistance profiles and documenting resistance gene combinations in clinical isolates.
Antibiotic Resistance Mechanism InvestigationView internship →
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